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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNIP
All Species:
17.88
Human Site:
T83
Identified Species:
43.7
UniProt:
Q9H3M7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3M7
NP_006463.3
391
43661
T83
L
L
L
E
D
Q
P
T
G
E
N
E
M
V
I
Chimpanzee
Pan troglodytes
XP_001156564
391
43626
T83
L
L
L
E
D
Q
P
T
G
E
N
E
M
V
I
Rhesus Macaque
Macaca mulatta
XP_001092636
391
43625
T83
L
L
P
E
D
Q
P
T
G
E
N
E
M
V
I
Dog
Lupus familis
XP_533037
391
43664
T83
L
L
L
E
D
Q
P
T
G
E
N
E
M
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG60
397
44345
A84
L
L
E
E
Q
P
T
A
G
E
N
E
M
V
I
Rat
Rattus norvegicus
Q5M7W1
394
43999
T83
L
L
L
E
D
Q
P
T
G
E
N
E
M
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510080
466
51563
D96
I
G
H
E
R
D
D
D
N
S
E
E
G
L
N
Chicken
Gallus gallus
XP_424699
414
46208
D96
I
G
H
E
R
D
D
D
N
S
E
E
G
L
H
Frog
Xenopus laevis
NP_001086622
388
42878
L80
L
Q
V
D
D
Q
P
L
D
S
D
G
S
V
L
Zebra Danio
Brachydanio rerio
NP_956381
400
44467
D86
Q
L
D
E
H
P
T
D
N
D
G
S
V
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.2
97.4
N.A.
94.9
96.4
N.A.
37.5
40.8
75.6
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.7
99.2
N.A.
97.4
98.2
N.A.
54.2
59.9
86.4
76.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
66.6
100
N.A.
13.3
13.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
66.6
100
N.A.
26.6
26.6
60
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
60
20
20
30
10
10
10
0
0
0
0
% D
% Glu:
0
0
10
90
0
0
0
0
0
60
20
80
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
0
0
60
0
10
10
20
0
0
% G
% His:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
20
0
0
0
0
0
0
0
0
0
0
0
0
10
60
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
70
70
40
0
0
0
0
10
0
0
0
0
0
20
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
30
0
60
0
0
0
10
% N
% Pro:
0
0
10
0
0
20
60
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
10
60
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
30
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
20
50
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _